Effect of catalytic alkali metal bromide on Hofmann-type rearrangement of imides.

نویسندگان

  • Katsuhiko Moriyama
  • Kazuma Ishida
  • Hideo Togo
چکیده

The Hofmann-type rearrangement of aromatic and aliphatic imides using KBr as the catalyst proceeded to provide aromatic and aliphatic amino acid derivatives. We have also developed a new synthetic route to gabapentin with this method.

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عنوان ژورنال:
  • Chemical communications

دوره 48 68  شماره 

صفحات  -

تاریخ انتشار 2012